KCNQ1 Antibody - 100µg
The KCNQ1 Antibody – 100 µg is a high-specificity, affinity-purified polyclonal antibody developed for the detection of KCNQ1 (Kv7.1), a voltage-gated potassium channel subunit critical in cardiac repolarization, epithelial ion transport, and inner ear development.
Validated for use in Western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF), this antibody is ideal for researchers studying long QT syndrome, electrophysiology, and channelopathies.
🔬 Key Features
- ✅ Recognizes human, mouse, and rat KCNQ1
- ✅ Purified from serum via protein A affinity chromatography
- ✅ Supplied in 100 µg aliquot for flexible assay use
- ✅ Validated for WB, IHC-P, and IF
- ✅ Available with BSA-free or azide-free formulations on request
📊 Technical Specifications
| Attribute | Details |
|---|---|
| Antigen | KCNQ1 (Potassium Voltage-Gated Channel Q1) |
| Gene ID | KCNQ1 – NCBI 3784 |
| Host Species | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC-P, IF |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Protein A Affinity |
| Concentration | 1 mg/mL |
| Volume | 100 µL |
| Supplied As | Lyophilized or Liquid Form (TE, pH 7.4) |
| Storage Conditions | –20°C (long-term); 4°C (short-term use) |
Cet anticorps sera garantie pour WB en France par Gentaur Laboratoire.
Référence interne:
ABD7568
URL de site web:
/shop/abd7568-kcnq1-antibody-100mg-7009
🧬 Background: What Is KCNQ1?
KCNQ1, also known as KvLQT1, encodes a potassium ion channel subunit that plays a critical role in cardiac action potential repolarization. Mutations in KCNQ1 are associated with:
- Type 1 Long QT Syndrome (LQT1)
- Familial Atrial Fibrillation
- Jervell and Lange-Nielsen Syndrome
Expression is also found in epithelial tissues including the kidney, colon, pancreas, and inner ear.
🧫 Application Data
- Western Blot (WB): 1:1,000 dilution recommended for lysates from heart, kidney, or epithelial tissues
- IHC (Paraffin-embedded): 1:200 dilution after antigen retrieval
- Immunofluorescence (IF): 1:250 for confocal microscopy of membrane localization
🧠 Frequently Asked Questions (FAQ)
Here are some common questions about our company.
A: No, this antibody was epitope-verified to be specific for KCNQ1 with no cross-reactivity with other KCNQ subtypes.
A: Yes, it is highly effective for probing KCNQ1 expression changes in Long QT syndrome models.
A: Yes, we support OEM, bulk orders, and preclinical-grade production upon request.